UP Manila is the health sciences center of the UP System. Its campus is spread out in the Ermita area as well as in three provinces. The Ermita, Manila area has the following: College of Arts & Sciences (CAS), National Teacher Training Center for the Health Professions (NTTC-HP), Office of the University Registrar (OUR) in Padre Faura Street (bounded by Ma. Orosa Street and Taft Avenue); Philippine General Hospital (PGH) in Taft Avenue; the Colleges of Dentistry (CD), Allied Medical Professions (CAMP), Nursing (CN), Public Health (CPH), and Medicine (CM) at Pedro Gil Street (between Taft Avenue and Adriatico St.); and, the UPM National Institutes of Health (UPM-NIH), also along Pedro Gil St.
It also has a UP School of Health Sciences in Palo, Leyte (after Typhoon Yolanda, temporarily located at the UP Tacloban campus); Baler, Aurora; and Koronadal in South Cotabato.