The Ramon Teves Pastor Memorial – Dumaguete Science High School, located at Maria Asuncion Village, Daro, Dumaguete City was founded and established in 1988 per Ordinance No. 81, Resolution No. 6 dated August 10, 1988, upon the recommendation of the Board of Directors of the Dumaguete Science Foundation, Inc. which is the resourcing arm of the school to maintain and sustain its operation.
On July 21, 1993, the RTPM – Dumaguete Science High School was integrated into the national roll by virtue of DECS Order No. 69, s. 1993 as among the thirteen Regional Science High Schools throughout the country (now already sixteen regions). The financing scheme is now under the authority of the Regional Director of DepEd, Central Visayas. The Local Government however, signified its commitment to continuously support the school in its physical development. This placed the school at an advantage, as receiving both local and national aid.